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Article

GBA-Associated Parkinson's Disease and Other Synucleinopathies.

Current neurology and neuroscience reports - 8 Jun 2018

Gan-Or Ziv, Liong Christopher, Alcalay Roy N

Abstract excerpt

PURPOSE OF REVIEW: GBA mutations are the most common known genetic cause of Parkinson's disease (PD). Its biological pathway may be important in idiopathic PD, since activity of the enzyme encoded by GBA, glucocerebrosidase, is reduced even among PD patients without GBA mutations. This article describes the structure and function of GBA, reviews recent literature on the clinical phenotype of GBA PD, and suggests...

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Source

Identifiers

PMID: 29884970
DOI: 10.1007/s11910-018-0860-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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