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Article

Association between autophagy and KRAS mutation with clinicopathological variables in colorectal cancer patients.

The Malaysian journal of pathology - 1 Aug 2021

Awi N J, Yap H Y, Armon S, Low J S H, Peh K B, Peh S C, Lee C S, Teow S Y

Abstract excerpt

Autophagy is a host defensive mechanism responsible for eliminating harmful cellular components through lysosomal degradation. Autophagy has been known to either promote or suppress various cancers including colorectal cancer (CRC). KRAS mutation serves as an important predictive marker for epidermal growth factor receptor (EGFR)-targeted therapies in CRC. However, the relationship between autophagy and KRAS...

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PMID: 34448791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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