Article
Determination of autophagy gene ATG16L1 polymorphism in human colorectal cancer.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie - 1 Jan 2014
Nicoli Elena Raluca, Dumitrescu Theodor, Uscatu Constantin Daniel, Popescu Florin Dan, Streaţă Ioana, Serban Şoşoi Simona, Ivanov Petar, Dumitrescu Alexandra, Bărbălan Alexandru, Lungulescu Dan, Petrescu Florin, Schenker Michael, Verdeş Doina, Săftoiu Adrian
Abstract excerpt
Autophagy has emerged not only as an essential repair mechanism to degrade damaged organelles and proteins but also as a major player in protection of tumor cells from multiple stresses. It was shown that autophagy gene polymorphisms are correlated with development of chronic inflammatory lesions, which represent a risk factor for colorectal tumors. In this study, we aimed to determine if ATG16L1 +898A>G...
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