Article
Detection of KRAS mutations and their associations with clinicopathological features and survival in Chinese colorectal cancer patients.
The Journal of international medical research - 1 Jan 2012
Li Z, Chen Y, Wang D, Wang G, He L, Suo J
Abstract excerpt
OBJECTIVE: Mutation of the KRAS (v-Kiras2 Kirsten rat sarcoma viral oncogene homologue) gene plays an important role in colorectal tumorigenesis. This study examined associations between KRAS gene mutations and clinicopathological and survival data in Chinese patients with colorectal cancer (CRC). METHODS: CRC patients were recruited for the detection of KRAS gene mutations using polymerase chain reaction and...
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