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Frailty and the risk of dementia: is the association explained by shared environmental and genetic factors?

17 Oct 2021

Abstract excerpt

BACKGROUND: Frailty has been identified as a risk factor for cognitive impairment and dementia. However, it is not known whether familial factors, such as genetics and shared environmental factors, underlie this association. We analyzed the association between frailty and the risk of dementia in a large twin cohort and examined the role of familial factors in the association. METHODS: The Rockwood frailty index...

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PMID: 34657626
DOI: 10.1186/s12916-021-02104-3

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