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Article

Identifying causal models between genetically regulated methylation patterns and gene expression in healthy colon tissue.

Clinical epigenetics - 21 Aug 2021

Díez-Villanueva Anna, Jordà Mireia, Carreras-Torres Robert, Alonso Henar, Cordero David, Guinó Elisabet, Sanjuan Xavier, Santos Cristina, Salazar Ramón, Sanz-Pamplona Rebeca, Moreno Victor

Abstract excerpt

BACKGROUND: DNA methylation is involved in the regulation of gene expression and phenotypic variation, but the inter-relationship between genetic variation, DNA methylation and gene expression remains poorly understood. Here we combine the analysis of genetic variants related to methylation markers (methylation quantitative trait loci: mQTLs) and gene expression (expression quantitative trait loci: eQTLs) with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34419169
DOI: 10.1186/s13148-021-01148-9
PMCID: PMC8380335

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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