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Article

DAXX represents a new type of protein-folding enabler.

Nature - 1 Sept 2021

Huang Liangqian, Agrawal Trisha, Zhu Guixin, Yu Sixiang, Tao Liming, Lin JiaBei, Marmorstein Ronen, Shorter James, Yang Xiaolu

Abstract excerpt

Protein quality control systems are crucial for cellular function and organismal health. At present, most known protein quality control systems are multicomponent machineries that operate via ATP-regulated interactions with non-native proteins to prevent aggregation and promote folding1, and few systems that can broadly enable protein folding by a different mechanism have been identified. Moreover, proteins that...

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Identifiers

PMID: 34408321
DOI: 10.1038/s41586-021-03824-5
PMCID: PMC8485697

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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