Article

BAG6 and RNF126 are broadly involved in protein quality control of non-native missense protein variants

2026-02-04

Abstract excerpt

Protein quality control (PQC) degradation is a vigorous and selective system that limits the accumulation of harmful, non-native and aggregation-prone proteins. Specific PQC pathways have been described for misfolded ER proteins, aberrant translational products and mislocalized proteins. However, many components involved in PQC of structurally unstable cytosolic proteins are unknown despite such proteins being a c...

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Literature Corpus work: 3a84b100-54de-5ff4-bb00-92303e7d8a7f
DOI: 10.64898/2026.02.04.703735

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