Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Recurrent loss of chromosome 22 and SMARCB1 deletion in extra-axial chordoma: A clinicopathological and molecular analysis.

Genes, chromosomes & cancer - 1 Dec 2021

Wen Xiaoyun, Cimera Robert, Aryeequaye Ruth, Abhinta Mohanty, Athanasian Edward, Healey John, Fabbri Nicola, Boland Patrick, Zhang Yanming, Hameed Meera

Abstract excerpt

Extra-axial chordoma is a rare neoplasm of extra-axial skeleton and soft tissue that shares identical histomorphologic and immunophenotypic features with midline chordoma. While genetic changes in conventional chordoma have been well-studied, the genomic alterations of extra-axial chordoma have not been reported. It is well known that conventional chordoma is a tumor with predominantly non-random copy number...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brachyury Protein
Share to Chromosome Deletion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosomes, Human, Pair 22

Share to Fetal Proteins

Share to Gene Deletion

Share to In Situ Hybridization, Fluorescence

Share to SMARCB1 Protein

Share to T-Box Domain Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 34392582
DOI: 10.1002/gcc.22992
PMCID: PMC8511200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Recurrent loss of chromosome 22 and SMARCB1 deletion in extra-axial chordoma: A clinicopathological and molecular analysis.PMID 34392582Read ↗

Molecular characteristics of poorly differentiated chordomaSemantic proximity Read ↗

Chordoma: Genetics and Contemporary Management.Semantic proximity Read ↗

Genomic aberrations frequently alter chromatin regulatory genes in chordoma.Semantic proximity Read ↗

SMARCA2‐NR4A3 is a novel fusion gene of extraskeletal myxoid chondrosarcoma identified by RNA next‐generation sequencingSemantic proximity Read ↗

Unique mutation portraits and frequent COL2A1 gene alteration in chondrosarcoma.Semantic proximity Read ↗

Genomic profiles and clinical presentation of chordoma.Semantic proximity Read ↗

From Histology to Multi-Omics: Review of Chordoma Classification and Its Clinical ImplicationsSemantic proximity Read ↗

Genome-wide DNA methylation profiling of recurrent and non-recurrent chordomasSemantic proximity Read ↗

Mutational analysis of primary and advanced chordoma tissue using next‐generation sequencingSemantic proximity Read ↗

Genomic Profiling of Low-grade Intramedullary Cartilage Tumors Can Distinguish Enchondroma From Chondrosarcoma.Semantic proximity Read ↗

Unraveling molecular advancements in chordoma tumorigenesis and treatment response: a review of scientific discoveries and clinical implicationsSemantic proximity Read ↗

SMARCB1/INI1 Involvement in Pediatric ChordomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.