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Article

Studying the effect of alpha-synuclein and Parkinson's disease linked mutants on inter pathway connectivities.

Scientific reports - 11 Aug 2021

Sen Sagnik, Dey Ashmita, Maulik Ujjwal

Abstract excerpt

Parkinson's disease is a common neurodegenerative disease. The differential expression of alpha-synuclein within Lewy Bodies leads to this disease. Some missense mutations of alpha-synuclein may resultant in functional aberrations. In this study, our objective is to verify the functional adaptation due to early and late-onset mutation which can trigger or control the rate of alpha-synuclein aggregation. In this...

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Identifiers

PMID: 34381149
DOI: 10.1038/s41598-021-95889-5
PMCID: PMC8358055

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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