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Article

Exploring Intrinsic Disorder in Human Synucleins and Associated Proteins.

International journal of molecular sciences - 1 Aug 2024

Venati Sriya Reddy, Uversky Vladimir N

Abstract excerpt

In this work, we explored the intrinsic disorder status of the three members of the synuclein family of proteins-α-, β-, and γ-synucleins-and showed that although all three human synucleins are highly disordered, the highest levels of disorder are observed in γ-synuclein. Our analysis of the peculiarities of the amino acid sequences and modeled 3D structures of the human synuclein family members revealed that the...

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Identifiers

PMID: 39125972
DOI: 10.3390/ijms25158399
PMCID: PMC11313516

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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