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Article

Understanding Genetic Risks: Computational Exploration of Human β-Synuclein nsSNPs and their Potential Impact on Structural Alteration.

Neuroscience letters - 11 Jun 2024

Mahur Pragati, Sharma Abhishek, Jahan Gulnaz, S G Adithya, Kumar Singh Amit, Muthukumaran Jayaraman, Jain Monika

Abstract excerpt

Synucleins are pivotal in neurodegenerative conditions. Beta-synuclein (β-synuclein) is part of the synuclein protein family alongside alpha-synuclein (α-synuclein) and gamma-synuclein (γ-synuclein). These proteins, found mainly in brain tissue and cancers, are soluble and unstructured. β-synuclein shares significant similarity with α-synuclein, especially in their N-terminus, with a 90% match. However, their...

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PMID: 38768940
DOI: 10.1016/j.neulet.2024.137826

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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