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Article

A microRNA panel compared to environmental and polygenic scores for colorectal cancer risk prediction.

Nature communications - 10 Aug 2021

Raut Janhavi R, Schöttker Ben, Holleczek Bernd, Guo Feng, Bhardwaj Megha, Miah Kaya, Schrotz-King Petra, Brenner Hermann

Abstract excerpt

Circulating microRNAs (miRNAs) could improve colorectal cancer (CRC) risk prediction. Here, we derive a blood-based miRNA panel and evaluate its ability to predict CRC occurrence in a population-based cohort of adults aged 50-75 years. Forty-one miRNAs are preselected from independent studies and measured by quantitative-real-time-polymerase-chain-reaction in serum collected at baseline of 198 participants who...

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Identifiers

PMID: 34376648
DOI: 10.1038/s41467-021-25067-8
PMCID: PMC8355103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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