Article
A novel SNP in promoter region of RP11-3N2.1 is associated with reduced risk of colorectal cancer.
Journal of human genetics - 1 Jan 2018
Ye Ding, Hu Yunqing, Jing Fangyuan, Li Yingjun, Gu Simeng, Jiang Xiyi, Mao Yingying, Li Qilong, Jin Mingjuan, Chen Kun
Abstract excerpt
Single-nucleotide polymorphisms (SNPs) in the promoter region of long intergenic non-coding RNAs (lincRNAs) could play a regulatory role in its expression level and then get involved in colorectal cancer (CRC). Thus, we conducted a two-stage case-control study to investigate the associations of Tag SNPs within the promoter region of selected lincRNAs from microarray data with risk of CRC. A total of 320 cases and...
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