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Article

External Validation of Risk Prediction Models Incorporating Common Genetic Variants for Incident Colorectal Cancer Using UK Biobank.

Cancer prevention research (Philadelphia, Pa.) - 1 Jun 2020

Saunders Catherine L, Kilian Britt, Thompson Deborah J, McGeoch Luke J, Griffin Simon J, Antoniou Antonis C, Emery Jon D, Walter Fiona M, Dennis Joe, Yang Xin, Usher-Smith Juliet A

Abstract excerpt

The aim of this study was to compare and externally validate risk scores developed to predict incident colorectal cancer that include common genetic variants (SNPs), with or without established lifestyle/environmental (questionnaire-based/classical/phenotypic) risk factors. We externally validated 23 risk models from a previous systematic review in 443,888 participants ages 37 to 73 from the UK Biobank cohort who...

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Identifiers

PMID: 32071122
DOI: 10.1158/1940-6207.CAPR-19-0521
PMCID: PMC7610623

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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