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Article

Oncogene activation in malignant transformation: a study of H-ras in human breast cancer.

Anticancer research - 1 Jan 2000

Spandidos D A

Abstract excerpt

Two types of oncogene activation can occur in tumors. Quantitative changes have been demonstrated in a variety of animal and human tumors using molecular hybridization and immunohistochemical analyses. Qualitative changes in oncogene expression have also been found in a variety of tumors. In this study the existence of point mutations and other genetic changes in the H-ras1 gene in human breast tumors is...

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PMID: 3435051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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