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Article

Depiction of the genomic and genetic landscape identifies CCL5 as a protective factor in colorectal neuroendocrine carcinoma.

British journal of cancer - 1 Sept 2021

Chen Dong, Bao Xuanwen, Zhang Ruyi, Ding Yongfeng, Zhang Min, Li Benfeng, Zhang Hangyu, Li Xiaolin, Tong Zhou, Liu Lulu, Zhou Xiaohu, Wang Saisai, Cheng Xiaofei, Zheng Yi, Ruan Jian, Fang Weijia, Zhao Peng

Abstract excerpt

BACKGROUND: Colorectal neuroendocrine carcinomas (CRNECs) are highly aggressive tumours with poor prognosis and low incidence. To date, the genomic landscape and molecular pathway alterations have not been elucidated. METHODS: Tissue sections and clinical information of CRNEC (n = 35) and CR neuroendocrine tumours (CRNETs) (n = 25) were collected as an in-house cohort (2010-2020). Comprehensive genomic and...

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Share to Carcinoma, Neuroendocrine
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34331023
DOI: 10.1038/s41416-021-01501-y
PMCID: PMC8476633

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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