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Article

Whole-exome sequencing of rectal neuroendocrine tumors.

Endocrine-related cancer - 1 Sept 2023

Li Yuanliang, Guo Yiying, Cheng Zixuan, Tian Chao, Chen Yingying, Chen Ruao, Yu Fuhuan, Shi Yanfen, Su Fei, Zhao Shuhua, Wang Zhizheng, Luo Jie, Tan Huangying

Abstract excerpt

The genetic characteristics of rectal neuroendocrine tumors (R-NETs) were poorly understood. Depicting the genetic characteristics may provide a biological basis for prognosis prediction and novel treatment development. Tissues of 18 R-NET patients were analyzed using whole-exome sequencing. The median tumor mutation burden (TMB) and microsatellite instability (MSI) were 1.15 Muts/MB (range, 0.03-23.28) and 0.36...

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Source

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Identifiers

PMID: 36645718
DOI: 10.1530/ERC-22-0257
PMCID: PMC10450454

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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