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Article

Comprehensive analysis of mutational and clinicopathologic characteristics of poorly differentiated colorectal neuroendocrine carcinomas.

Scientific reports - 18 Mar 2021

Lee Sun Mi, Sung Chang Ohk

Abstract excerpt

Poorly differentiated neuroendocrine carcinoma (NEC) is a rare subtype of colorectal cancer (CRC). This study aimed to investigate clinicopathologic characteristics of colorectal NECs and elucidate genomic differences and similarities between colorectal NECs and colorectal adenocarcinomas (ACs). A total of 30 colorectal NECs were screened for frequently identified CRC oncogenic driver genes by targeted...

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Adenomatous Polyposis Coli Protein
Carcinoma, Neuroendocrine
Class I Phosphatidylinositol 3-Kinases
Lymphatic Metastasis
Microsatellite Instability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Neoplasm Grading

Retinoblastoma Binding Proteins

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Identifiers

PMID: 33737597
DOI: 10.1038/s41598-021-85593-9
PMCID: PMC7973429

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