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CCR5 and CCL5 gene expression in colorectal cancer: comprehensive profiling and clinical value

1 Jan 2024

Abstract excerpt

Background The C-C motif chemokine receptor 5 (CCR5)/C-C motif chemokine ligand 5 (CCL5) axis plays a major role in colorectal cancer (CRC). We aimed to characterize the molecular features associated with CCR5 / CCL5 expression in CRC and to determine whether CCR5 / CCL5 levels could impact treatment outcomes. Methods 7604 CRCs tested with NextGen Sequencing on DNA and RNA were analyzed. Molecular features were...

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PMID: 38212126
DOI: 10.1136/jitc-2023-007939

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