Article
The Mutational, Prognostic, and Therapeutic Landscape of Neuroendocrine Neoplasms.
The oncologist - 7 Sept 2023
Liu Man, Li Na, Tang Hongzhen, Chen Luohai, Liu Xuemei, Wang Yu, Lin Yuan, Luo Yanji, Wei Shaozhen, Wen Wenli, Chen Minhu, Wang Jiaqian, Zhang Ning, Chen Jie
Abstract excerpt
BACKGROUND: Neuroendocrine neoplasms (NENs) represent clinically and genetically heterogeneous malignancies, thus a comprehensive understanding of underlying molecular characteristics, prognostic signatures, and potential therapeutic targets is urgently needed. METHODS: Next-generation sequencing (NGS) and immunohistochemistry were applied to acquire genomic and immune profiles of NENs from 47 patients. RESULTS:...
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