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Article

Phase Separation of MAGI2-Mediated Complex Underlies Formation of Slit Diaphragm Complex in Glomerular Filtration Barrier.

Journal of the American Society of Nephrology : JASN - 1 Aug 2021

Zhang Haijiao, Lin Lin, Liu Jianping, Pan Lifeng, Lin Zhijie, Zhang Mingjie, Zhang Jiong, Cao Ying, Zhu Jinwei, Zhang Rongguang

Abstract excerpt

BACKGROUND: Slit diaphragm is a specialized adhesion junction between the opposing podocytes, establishing the final filtration barrier to urinary protein loss. At the cytoplasmic insertion site of each slit diaphragm there is an electron-dense and protein-rich cellular compartment that is essential for slit diaphragm integrity and signal transduction. Mutations in genes that encode components of this...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 34330769
DOI: 10.1681/ASN.2020111590
PMCID: PMC8455267

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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