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Article

MAGI-2 is critical for the formation and maintenance of the glomerular filtration barrier in mouse kidney.

The American journal of pathology - 1 Oct 2014

Ihara Kan-Ichiro, Asanuma Katsuhiko, Fukuda Tomokazu, Ohwada Shyuichi, Yoshida Midori, Nishimori Katsuhiko

Abstract excerpt

Membrane-associated guanylate kinase inverted 2 (MAGI-2) is a tight junction protein in epithelial tissues. We previously reported the detailed expression patterns of MAGI-2 in mouse tissues, including kidney podocytes, based on results obtained from Venus knock-in mice for Magi2 locus. In the present study, homozygous deletion of the Magi2 gene in mice caused neonatal lethality, which was explained by podocyte...

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Identifiers

PMID: 25108225
DOI: 10.1016/j.ajpath.2014.06.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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