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Article

Role of podocyte slit diaphragm as a filtration barrier (Review Article)

21 Jul 2006

Abstract excerpt

Although the role of glomerular basement membrane has been emphasised as the barrier for retaining plasma proteins in the past three decades, some recent studies have demonstrated that the slit diaphragm of the glomerular epithelial cell (podocyte) is the structure likely to be the barrier in the glomerular capillary wall. Nephrin and podocin were identified as gene products mutated in Finnish-type congenital...

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PMID: 16889564
DOI: 10.1111/j.1440-1797.2006.00583.x

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