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Article

Transcriptional landscape of PTEN loss in primary prostate cancer

26 Jul 2021

Abstract excerpt

BACKGROUND: PTEN is the most frequently lost tumor suppressor in primary prostate cancer (PCa) and its loss is associated with aggressive disease. However, the transcriptional changes associated with PTEN loss in PCa have not been described in detail. In this study, we highlight the transcriptional changes associated with PTEN loss in PCa. METHODS: Using a meta-analysis approach, we leveraged two large PCa...

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PMID: 34311724
DOI: 10.1186/s12885-021-08593-y

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