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Associations of genetically predicted circulating insulin-like growth factor-1 and insulin-like growth factor binding protein-3 with bladder cancer risk.

Molecular carcinogenesis - 1 Nov 2021

Tsai Chia-Wen, Chang Wen-Shin, Xu Yifan, Huang Maosheng, Bau Da-Tian, Gu Jian

Abstract excerpt

Insulin-like growth factors (IGF) play important roles in carcinogenesis. The associations of circulating IGF-1 and insulin-like growth factor-binding protein-3 (IGFBP-3) with the risks of bladder cancer remain unclear. In this large case control study of 2011 bladder cancer cases and 2369 heathy controls, we assessed the associations of circulating IGF-1 and IGFBP-3 with bladder cancer risks using a Mendelian...

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PMID: 34293213
DOI: 10.1002/mc.23334

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