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Article

Genetic variation in IGF1 predicts renal cell carcinoma susceptibility and prognosis in Chinese population.

Scientific reports - 15 Dec 2016

Cao Qiang, Liang Chao, Xue Jianxin, Li Pu, Li Jie, Wang Meilin, Zhang Zhengdong, Qin Chao, Lu Qiang, Hua Lixin, Shao Pengfei, Wang Zengjun

Abstract excerpt

Insulin-like growth factor 1 (IGF1) and IGF binding protein 3 (IGFBP3) play an important role in the development and progression of renal cell carcinoma (RCC). We evaluated the association of functional polymorphisms in IGF1 and IGFBP3 with susceptibility and prognosis of RCC. We genotyped nine potentially functional polymorphisms in IGF1 and IGFBP3 and assessed their association with risk of RCC in a two-stage...

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Source

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Identifiers

PMID: 27976731
DOI: 10.1038/srep39014
PMCID: PMC5157037

Genes

IGF1
IGFBP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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