Article
Association between two functional polymorphisms of insulin-like growth factor binding protein 3 and colorectal cancer risk in a Chinese population.
Journal of toxicology and environmental health. Part A - 1 Jan 2009
Xiang Hao, Liu Li, Chu Guang-di, Wei Sheng, Liu Jian-ping, Xu Yi-hua, Chen Ji-gui, Wang Chong-jian, Wei Qing-Yi, Nie Shao-fa
Abstract excerpt
Circulating levels of insulin-like growth factor binding protein 3 (IGFBP3) are modulated by functional variants of IGFBP3 and therefore may be associated with higher risk of colorectal cancer development. However, few studies have investigated the role of IGFBP3 polymorphisms in colorectal cancer in Chinese individuals. In this study, two common polymorphisms of IGFBP3 were determined by the Taqman genotyping...
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