Article
Significance of Mitochondrial DNA Haplogroup on Epidermal Growth Factor Receptor Mutation in Japanese Patients With Lung Adenocarcinoma.
Anticancer research - 1 Aug 2021
Otsuka Tsunayuki, Ueda Kazuhiro, Furukawa Tatsuhiko, Koriyama Chihaya, Inoue Ituro, Sato Masami
Abstract excerpt
BACKGROUND/AIM: The frequency of somatic mutations of epidermal growth factor receptor (EGFR) in primary lung adenocarcinoma varies among populations and countries. The aim of the present study was to clarify whether the frequency of EGFR mutations in patients with lung adenocarcinoma depends on their mitochondrial DNA haplogroup, which reflects their maternal lineage. PATIENTS AND METHODS: Using normal lung...
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