Article
Mitochondrial DNA haplogroups and somatic mutations are associated with lung cancer in patients from Southwest China.
Genetics and molecular research : GMR - 12 May 2015
Fang Y, Yang H Y, Shi Y H, Cui J H, Li L Y, Xu Y C, Shao J L
Abstract excerpt
Mitochondrial DNA mutations play crucial roles in the pathogenesis and progression of human malignancies. Therefore, to determine whether maternal background or mitochondrial DNA somatic mutations were essential cofactors in the lung cancer of Chinese patients as well, the complete mitochondrial DNA displacement loop of the primary cancerous, matched para-cancerous normal and distant normal tissues for 79 Chinese...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.