Article
Cancer type-specific modulation of mitochondrial haplogroups in breast, colorectal and thyroid cancer.
BMC cancer - 12 Aug 2010
Fang Hezhi, Shen Lijun, Chen Tao, He Jing, Ding Zhinan, Wei Jia, Qu Jianchun, Chen Guorong, Lu Jianxin, Bai Yidong
Abstract excerpt
BACKGROUND: Mitochondrial DNA (mtDNA) haplogroups and single nucleotide polymorphisms (mtSNP) have been shown to play a role in various human conditions including aging and some neurodegenerative diseases, metabolic diseases and cancer. METHODS: To investigate whether mtDNA haplogroups contribute to the occurrence of cancer in a specific Chinese population, we have carried out a comprehensive case-control study...
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