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Article

Female-specific association among I, J and K mitochondrial genetic haplogroups and cancer: A longitudinal cohort study.

Cancer genetics - 1 Aug 2018

Luchini Claudio, Nottegar Alessia, Vaona Alberto, Stubbs Brendon, Demurtas Jacopo, Maggi Stefania, Veronese Nicola

Abstract excerpt

Recent studies highlighted the role of mitochondrial dysregulation in cancer, suggesting that the different mitochondrial haplogroups might play a role in tumorigenesis and risk of cancer development. Our aim is to investigate whether any mitochondrial haplogroups carried a significant higher risk of cancer development in a large prospective cohort of North American people. The haplogroup assignment was performed...

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Identifiers

PMID: 29778233
DOI: 10.1016/j.cancergen.2018.04.003
PMCID: PMC5973548

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