Article
Tumorigenic effect of TERT and its potential therapeutic target in NSCLC (Review).
Oncology reports - 1 Aug 2021
Yang Liu, Li Na, Wang Meng, Zhang Yan-Hua, Yan Lu-Da, Zhou Wen, Yu Zhi-Qiong, Peng Xiao-Chun, Cai Jun
Abstract excerpt
Non‑small cell lung cancer (NSCLC), which accounts for ~85% of all lung cancer cases, is commonly diagnosed at an advanced stage and has a high patient mortality rate. Despite the increasing availability of treatment strategies, the prognosis of patients with NSCLC remains poor, with a low 5‑year survival rate. This poor prognosis may be associated with the tumor heterogeneity of NSCLC, as well as its acquisition...
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