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Targeting telomerase for its advent in cancer therapeutics

11 May 2020

Abstract excerpt

Telomerase has emerged as an important primary target in anticancer therapy. It is a distinctive reverse transcriptase enzyme, which extends the length of telomere at the 3' chromosomal end, and uses telomerase reverse transcriptase (TERT) and telomerase RNA template-containing domains. Telomerase has a vital role and is a contributing factor in human health, mainly affecting cell aging and cell proliferation....

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PMID: 32391613
DOI: 10.1002/med.21674

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