Article
Enhanced Susceptibility of Galectin-1 Deficient Mice to Experimental Colitis.
Frontiers in immunology - 1 Jan 2021
Fernandez-Perez Raquel, Lopez-Santalla Mercedes, Sánchez-Domínguez Rebeca, Alberquilla Omaira, Gutiérrez-Cañas Irene, Juarranz Yasmina, Bueren Juan A, Garin Marina I
Abstract excerpt
Galectin-1 is a β-galactoside-binding lectin, ubiquitously expressed in stromal, epithelial, and different subsets of immune cells. Galectin-1 is the prototype member of the galectin family which shares specificity with β-galactoside containing proteins and lipids. Immunomodulatory functions have been ascribed to endogenous galectin-1 due to its induction of T cell apoptosis, inhibitory effects of neutrophils and...
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