Article
Anti-inflammatory effect of galectin-1 in a murine model of atopic dermatitis.
Journal of molecular medicine (Berlin, Germany) - 1 Sept 2017
Corrêa Mab Pereira, Andrade Frans Eberth Costa, Gimenes Alexandre Dantas, Gil Cristiane Damas
Abstract excerpt
Atopic dermatitis (AD) is caused by both dysregulated immune responses and an impaired skin barrier. Although beta-galactoside-binding protein galectin-1 (Gal-1) has immunomodulatory effects in several inflammatory disorders, therapeutic strategies based on its anti-inflammatory properties have not been explored in AD. Thus, we evaluate pharmacological treatment with Gal-1 in the progression of an ovalbumin...
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