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Article

Galectin-3 suppresses mucosal inflammation and reduces disease severity in experimental colitis.

Journal of molecular medicine (Berlin, Germany) - 1 May 2016

Tsai Hwei-Fang, Wu Chien-Sheng, Chen Yi-Lin, Liao Hsiu-Jung, Chyuan I-Tsu, Hsu Ping-Ning

Abstract excerpt

UNLABELLED: Galectin-3, a member of the β-galactoside-binding lectin family, expresses in many different immune cells and modulates broad biological functions including cell adhesion, cell activation, cell growth, apoptosis, and inflammation. However, the role of galectin-3 in mucosal immunity or inflammatory bowel diseases is still not clear. We demonstrate here that galectin-3 knockout mice have more severe...

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Source

Identifiers

PMID: 26631140
DOI: 10.1007/s00109-015-1368-x

Genes

FOXP3
ICOS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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