Article
Galanin contributes to the excess colonic fluid secretion observed in dextran sulfate sodium murine colitis.
Inflammatory bowel diseases - 1 Jul 2004
Matkowskyj Kristina A, Nathaniel Rajkumar, Prasad Roli, Weihrauch Dirk, Rao Mrinalini, Benya Richard V
Abstract excerpt
Galanin is present in enteric nerves lining the gastrointestinal (GI) tract where it is normally involved in regulating intestinal motility by binding to the galanin-1 receptor (Gal1R) subtype expressed by smooth muscle cells. In contrast, although epithelial cells lining the colon do not normall...
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