Article
Galectin-1 is essential for efficient liver regeneration following hepatectomy.
Oncotarget - 31 May 2016
Potikha Tamara, Ella Ezra, Cerliani Juan P, Mizrahi Lina, Pappo Orit, Rabinovich Gabriel A, Galun Eithan, Goldenberg Daniel S
Abstract excerpt
Galectin-1 (Gal1) is a known immune/inflammatory regulator which acts both extracellularly and intracellularly, modulating innate and adaptive immune responses. Here, we explored the role of Gal1 in liver regeneration using 70% partial hepatectomy (PHx) of C57BL/6 wild type and Gal1-knockout (Gal1-KO, Lgals1-/-) mice. Gene or protein expression, in liver samples collected at time intervals from 2 to 168 hours...
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