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Article

Variants in mycophenolate and CMV antiviral drug pharmacokinetic and pharmacodynamic genes and leukopenia in heart transplant recipients.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 Sept 2021

Oreschak Kris, Saba Laura M, Rafaels Nicholas, Ambardekar Amrut V, Deininger Kimberly M, PageII RobertL, Lindenfeld JoAnn, Aquilante Christina L

Abstract excerpt

BACKGROUND: The objective was to assess the relationship between single nucleotide polymorphisms in mycophenolate and cytomegalovirus antiviral drug pharmacokinetic and pharmacodynamic genes and drug-induced leukopenia in adult heart transplant recipients. METHODS: This retrospective analysis included n = 148 patients receiving mycophenolate and a cytomegalovirus antiviral drug. In total, 81 single nucleotide...

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Identifiers

PMID: 34253456
DOI: 10.1016/j.healun.2021.05.020
PMCID: PMC8405578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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