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Article

Cyclosporine and methotrexate-related pharmacogenomic predictors of acute graft-versus-host disease.

Haematologica - 1 Feb 2015

Laverdière Isabelle, Guillemette Chantal, Tamouza Ryad, Loiseau Pascale, Peffault de Latour Regis, Robin Marie, Couture Félix, Filion Alain, Lalancette Marc, Tourancheau Alan, Charron Dominique, Socié Gérard, Lévesque Éric

Abstract excerpt

Effective immunosuppression is mandatory to prevent graft-versus-host disease and to achieve a successful clinical outcome of hematopoietic stem cell transplantation. Here we tested whether germline single nucleotide polymorphisms in 20 candidate genes related to methotrexate and cyclosporine metabolism and activity influence the incidence of graft-versus-host disease in patients who undergo stem cell...

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Identifiers

PMID: 25425682
DOI: 10.3324/haematol.2014.109884
PMCID: PMC4803136

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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