Article
Cyclosporine and methotrexate-related pharmacogenomic predictors of acute graft-versus-host disease.
Haematologica - 1 Feb 2015
Laverdière Isabelle, Guillemette Chantal, Tamouza Ryad, Loiseau Pascale, Peffault de Latour Regis, Robin Marie, Couture Félix, Filion Alain, Lalancette Marc, Tourancheau Alan, Charron Dominique, Socié Gérard, Lévesque Éric
Abstract excerpt
Effective immunosuppression is mandatory to prevent graft-versus-host disease and to achieve a successful clinical outcome of hematopoietic stem cell transplantation. Here we tested whether germline single nucleotide polymorphisms in 20 candidate genes related to methotrexate and cyclosporine met...
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