Article
The Impact of Genetic Polymorphisms on the Pharmacokinetics and Pharmacodynamics of Mycophenolic Acid: Systematic Review and Meta-analysis.
Clinical pharmacokinetics - 1 Oct 2021
Na Takuathung Mingkwan, Sakuludomkan Wannachai, Koonrungsesomboon Nut
Abstract excerpt
BACKGROUND: Mycophenolic acid (MPA) is among the most commonly prescribed medications for immunosuppression following organ transplantation. Highly variable MPA exposure and drug response are observed among individuals receiving the same dosage of the drug. Identification of candidate genes whose polymorphisms could be used to predict MPA exposure and clinical outcome is of clinical value. OBJECTIVES: This study...
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