Article
Post-transplant complications revealed by mycophenolate mofetil related transporters and metabolic enzymes gene polymorphisms in pediatric patients with hematological disorders.
BMC cancer - 18 Dec 2024
Ji Qi, Hu Yixin, Liu Minyuan, Liu Lixia, Zheng Jiajia, Du Zhizhuo, Gao Li, Xiao Peifang, Ling Jing, Fan Liyan, Bian Xinni, Lou Feng, Cao Shanbo, Li Jie, Tian Yuanyuan, Lu Jun, Qin Jiayue, Hu Shaoyan
Abstract excerpt
BACKGROUND: Haploidentical hematopoietic stem cell transplantation (Haplo-HSCT) serves as an important option for patients without an HLA matched donor in treating hematological disorders, while patients may experience various complications after transplantation. Mycophenolate mofetil (MMF), a cornerstone drug for graft-versus-host disease (GvHD) prophylaxis, effectively reduces the incidence of acute GvHD, and...
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