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Article

Mycophenolate mofetil-related leukopenia in children and young adults following kidney transplantation: Influence of genes and drugs.

Pediatric transplantation - 1 Nov 2017

Varnell Charles D, Fukuda Tsuyoshi, Kirby Cassie L, Martin Lisa J, Warshaw Barry L, Patel Hiren P, Chand Deepa H, Barletta Gina-Marie, Van Why Scott K, VanDeVoorde Rene G, Weaver Donald J, Wilson Amy, Verghese Priya S, Vinks Alexander A, Greenbaum Larry A, Goebel Jens, Hooper David K

Abstract excerpt

MMF is commonly prescribed following kidney transplantation, yet its use is complicated by leukopenia. Understanding the genetics mediating this risk will help clinicians administer MMF safely. We evaluated 284 patients under 21 years of age for incidence and time course of MMF-related leukopenia and performed a candidate gene association study comparing the frequency of 26 SNPs between cases with MMF-related...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28869324
DOI: 10.1111/petr.13033
PMCID: PMC5905326

Genes

IMPDH1

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