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Article

Influence of Genetic Polymorphisms on Mycophenolic Acid Pharmacokinetics and Patient Outcomes in Renal Transplantation.

Current drug metabolism - 1 Jan 2018

Guo Miao, Wang Zi-Jie, Yang Hai-Wei, Meng Ling, Tan Ruo-Yun, Gu Min, Wei Ji-Fu

Abstract excerpt

BACKGROUND: Mycophenolic Acid (MPA) is an immunosuppressive drug widely used in the treatment of organ transplantation and autoimmune diseases. Pharmacokinetics and pharmacodynamics of MPA varies between individuals, the potential reasons being the genetic polymorphisms in key enzymes, drug transporters and target proteins of MPA. OBJECTIVE: We try to provide pharmacogenomics information for drug selection and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29283068
DOI: 10.2174/1389200219666171227201608

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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