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Article

Genetic polymorphisms influence mycophenolate mofetil-related adverse events in pediatric heart transplant patients.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation - 1 May 2010

Ohmann Erin L, Burckart Gilbert J, Brooks Maria M, Chen Yan, Pravica Vera, Girnita Diana M, Zeevi Adriana, Webber Steven A

Abstract excerpt

BACKGROUND: Mycophenolate mofetil (MMF) is an effective and commonly used immunosuppressant but has frequent adverse events. Genetic polymorphisms may contribute to variability in MMF efficacy and related complications. In this study we explore the distribution frequencies of common single nucleotide polymorphisms (SNPs) of IMPDH1, IMPDH2 and ABCC2 and investigate whether these SNPs influence MMF adverse events...

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Source

Identifiers

PMID: 20061166
DOI: 10.1016/j.healun.2009.11.602

Genes

ABCC2
IMPDH1
IMPDH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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