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Article

K<sub>ATP</sub>Channels and Cardiovascular Disease

28 Mar 2013

Abstract excerpt

ATP-sensitive potassium (KATP) channels were first discovered in the heart 30 years ago. Reconstitution of KATP channel activity by coexpression of members of the pore-forming inward rectifier gene family (Kir6.1, KCNJ8, and Kir6.2 KCNJ11) with sulfonylurea receptors (SUR1, ABCC8, and SUR2, ABCC9) of the ABCC protein subfamily has led to the elucidation of many details of channel gating and pore properties. In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23538276
DOI: 10.1161/circresaha.112.300514

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