Article
Distinct nuclear compartment-associated genome architecture in the developing mammalian brain.
Nature neuroscience - 1 Sept 2021
Ahanger Sajad Hamid, Delgado Ryan N, Gil Eugene, Cole Mitchel A, Zhao Jingjing, Hong Sung Jun, Kriegstein Arnold R, Nowakowski Tomasz J, Pollen Alex A, Lim Daniel A
Abstract excerpt
Nuclear compartments are thought to play a role in three-dimensional genome organization and gene expression. In mammalian brain, the architecture and dynamics of nuclear compartment-associated genome organization is not known. In this study, we developed Genome Organization using CUT and RUN Technology (GO-CaRT) to map genomic interactions with two nuclear compartments-the nuclear lamina and nuclear...
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