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Article

The Prognostic Role of MYC Structural Variants Identified by NGS and FISH in Multiple Myeloma

7 Jul 2021

Abstract excerpt

PURPOSE: Structural variants (SV) of the MYC gene region are common in multiple myeloma and influence disease progression. However, the prognostic significance of different MYC SVs in multiple myeloma has not been clearly established. EXPERIMENTAL DESIGN: We conducted a retrospective study of multiple myeloma comparing MYC SV subtypes identified by next-generation sequencing (NGS) and FISH to MYC expression and...

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PMID: 34233962
DOI: 10.1158/1078-0432.ccr-21-0005

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