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Characterization of MYC Rearrangements in Multiple Myeloma: an Optical Genome Mapping Approach

20 Sept 2024

Abstract excerpt

Multiple myeloma (MM) is characterized by complex, heterogeneous genetic abnormalities that significantly affect disease progression, treatment response, and prognosis. Recurrent genetic alterations in MM include primary events such as immunoglobulin heavy chain (IGH) structural variations (SVs) and hyperdiploidy, and secondary events associated with disease progression, including 1q gain, 17p deletion, and MYC...

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Glycosylation and Glycoproteins Research
Multiple Myeloma Research and Treatments
Protein Degradation and Inhibitors

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39304649
DOI: 10.1038/s41408-024-01147-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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